Story and photo by R. Mascardo

SANTA CLARA — Josh Rosen of the Cardinals threw a 75-yar touchdown pass to fellow rookie Christian Kirk on Arizona’s first play from scrimmage. And the Cardinals used five take-aways to get their win, beating the San Francisco 49ers, 28-18 on Sunday.

The Cardinals were unable to do much more on offense the rest of the way, with their only other score coming on Josh Byrne’s fumble return for a TD and David Johnson TD runs on two short drive after turnovers by the 49ers.

But a San Francisco offense did little after an opening drive score behind back-up quarterback C.J. Beathard.

Rosen dropped back and launched a deep throw to Kirk who was wide open down the middle of the field because free safety Adrian Colbert took a bad angle on the play.

Patrick Peterson of the Cardinals recovered a fumble by Raheem Master and returned it 49 yards to the San Francisco 18, setting up David Johnson’s 2-yard run that made it 14-6.

The Niners finally scored again on a fourth-and-1 pass from Beathard to Trent Taylor with 6:51 to play. But the 49ers couldn’t convert the 2-point try.

The Cardinals took the game when Haason Reddick knocked the ball out of Beathard’s hand and Byanes returned it  for a 23- yard score that gave Arizona its seventh straight win in the series.

Cardinal’s rookie quarterback Josh Rosen got the win in his second start of the season despite completing just 10 of 25 pass for 170 yards.

NEXT: San Francisco 49ers visit Green bay on October 15.